Episode 1 : Mr. Monk Takes Manhattan
Monk, Sharona, Captain Stottlemeyer, and Lieutenant Disher arrive in New York City to pursue a lead in the murder case of Monk's wife, Trudy. Dale the Whale has given them the name of a man that was involved: Warrick Tennyson. But before they can even check into their hotel rooms, Monk becomes a witness in the shooting death of the Latvian Ambassador to the United States. Unfortunately, Monk only gets a glimpse of the killer's left ear as he flees the scene of the crime.
Episode 2 : Mr. Monk and the Panic Room
It's the middle of the night at the estate of eccentric record producer Ian Blackburn. Blackburn is in his home studio, working on some songs for his pop superstar wife, Chloe (Carmen Electra). An alarm goes off, and Blackburn grabs his pet chimpanzee, Darwin, and runs to his fortified panic room where, moments later, police arrive on the scene and blast their way in. They enter to discover an incredibly bizarre tableau: Blackburn shot dead with Darwin the chimp standing over him, covered in blood and holding a revolver. Stottlemeyer and Disher reluctantly hold Darwin as the prime suspect, but they quickly enlist the help of Monk to determine the guilt or innocence of this most unlikely simian suspect.
Episode 5 : Mr. Monk Meets the Godfather
When an unknown gunman shoots up a barbershop owned by the mob, Monk is called on by Salvatore Lucarelli (Phillip Baker Hall), the West Coast Godfather, to find the killer and prevent a mob war. Monk initially wants nothing to do with the Lucarelli family, but the Feds convince him to take the job and help bring down the entire organization.
Episode 7 : Mr. Monk and the Employee of the Month
It's almost dawn at a suburban "Mega-Mart" retail store, and the store's best employee, Edna Coruthers, arrives early for work. There's a note telling her to go to the loading dock, and when she gets there, a forklift rumbles toward her, knocking over a stack of TV sets. Poor Edna is crushed and killed. Captain Stottlemeyer and Lieutenant Disher investigate, and the case appears to be a routine industrial accident. But the store's security manager suspects foul play and calls Monk to the scene. It turns out the security manager is Joe Christie, Monk's ex-partner who was kicked off the force years ago for stealing drugs from an evidence room. Christie shows Monk some evidence, but Monk refuses to work with his crooked ex-partner.
Episode 9 : Mr. Monk Takes His Medicine
Captain Stottlemeyer and Lieutenant Disher are making a routine arrest when a mysterious man in a car drives up and shoots at them, wounding Stottlemeyer. With Stottlemeyer in the hospital, Monk joins Disher in an intense investigation. Their prime suspect is the man Stottlemeyer and Disher were trying to arrest at the time of the shooting, a biker who was attempting to skip bail. When Monk and Disher try to apprehend the biker, Monk's obsessive-compulsive disorder allows the suspect to escape. Consumed with guilt, Monk goes to Dr. Kroger (Stanley Kamel) for help. Dr. Kroger gives Monk some pills that help people with O.C.D., and Monk reluctantly tries them. The pills work, and soon Monk becomes a completely different person. He's more relaxed, and his fears and phobias seem to be gone. But despite the benefits, there's one key cost: Monk has lost his ability to solve crime.